Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670530 | 0.81 | L3MBTL1 (0.57) | HTTALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL8423468 | 0.81 | GPR35 (0.54) | HTTALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL21487311 | 0.78 | HTT (0.52) | HTTALDH1A1GAAMAPTTDP1 | |
| SCHEMBL6777847 | 0.78 | HTT (0.52) | HTTALDH1A1GAAMAPTTDP1 | |
| SCHEMBL5677351 | 0.77 | ENPP2 (0.49) | ALDH1A1GAAMAPTTDP1LMNA | |
| SCHEMBL13419245 | 0.76 | KMT2A (0.49) | ALDH1A1GAAL3MBTL1MAPTTDP1 | |
| SCHEMBL10628543 | 0.75 | GPR35 (0.67) | ALDH1A1GAAL3MBTL1MAPTTDP1 | |
| SCHEMBL27303263 | 0.75 | HTT (0.59) | HTTALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL7813230 | 0.74 | CASP6 (0.57) | ALDH1A1GAAL3MBTL1MAPTTDP1 | |
| SCHEMBL10825017 | 0.74 | HTT (0.52) | HTTALDH1A1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217304-A | Continuous reduction process | CIBA-GEIGY AG (CH) | 1980-08-12 | — | — | US | disclosed |