Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436157 | 0.77 | OPRM1 (0.36) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11436426 | 0.69 | MLYCD (0.42) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11450446 | 0.69 | POLB (0.45) | OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL11438624 | 0.67 | MLYCD (0.39) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11443811 | 0.67 | ALDH1A1 (0.39) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11446647 | 0.67 | TP53 (0.48) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11447557 | 0.66 | OPRM1 (0.50) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11437770 | 0.66 | ALDH1A1 (0.40) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11446508 | 0.66 | NPC1 (0.42) | OPRM1OPRK1OPRD1ALDH1A1KDM4E | |
| SCHEMBL11447586 | 0.65 | MITF (0.47) | OPRM1OPRK1OPRD1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |