Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464457 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HTTNPSR1LMNAHPGD | |
| SCHEMBL9056522 | 0.80 | ALDH5A1 (0.56) | ALDH1A1HTTLMNAHPGDTDP1 | |
| SCHEMBL4452292 | 0.80 | ALDH5A1 (0.56) | ALDH1A1HTTLMNAHPGDTDP1 | |
| SCHEMBL11490236 | 0.78 | MEN1 (0.53) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL12997454 | 0.78 | MEN1 (0.53) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4862884 | 0.78 | CES2 (0.50) | ALDH1A1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL1193448 | 0.78 | MEN1 (0.53) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8420807 | 0.78 | CES2 (0.50) | ALDH1A1NPSR1LMNAHPGDMAPT | |
| SCHEMBL14842658 | 0.78 | TPMT (0.48) | ALDH1A1HTTNPSR1LMNAHPGD | |
| SCHEMBL5469788 | 0.78 | CES2 (0.50) | ALDH1A1NPSR1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235741-A | OPTICAL BRIGHTENERS OF 2,4-BIS-(STILBEN-4'-YL)-V-TRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4217449-A | Process for the preparation of bis-triazolylstilbenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | disclosed |
| EP-0001582-B1 | PROCESS FOR THE PREPARATION OF BIS-TRIAZOLYL STILBENES | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0001582-A1 | Process for the preparation of bis-triazolyl stilbenes | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |