Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051691 | 0.83 | HDAC1 (0.39) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2606218 | 0.78 | HDAC1 (0.39) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL29505633 | 0.77 | CYP2A6 (0.47) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4588444 | 0.77 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL10465738 | 0.77 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4236815 | 0.77 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL1160196 | 0.77 | CYP2A6 (0.47) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2653187 | 0.76 | KDM4E (0.41) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2653189 | 0.76 | KDM4E (0.41) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2603490 | 0.74 | EGFR (0.52) | HDAC1MAPTKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009361-A1 | 2-Alkoxycarbonylamino benzimidazoles having a halogen-containing substituent, their preparation and their use as parasiticides | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | claimed |