Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437822 | 0.78 | MEN1 (0.42) | CHRM2CHRM3MEN1KMT2ASIGMAR1 | |
| SCHEMBL19707208 | 0.74 | KCNH2 (0.53) | KCNH2HRH3LMNAMEN1KMT2A | |
| SCHEMBL11579712 | 0.70 | TRPM8 (0.44) | CHRM2CHRM3TRPM8MEN1KMT2A | |
| SCHEMBL11500743 | 0.67 | TRPM8 (0.46) | TRPM8MEN1KMT2A | |
| SCHEMBL11442250 | 0.67 | TRPM8 (0.35) | LMNATRPM8MEN1KMT2A | |
| SCHEMBL18763039 | 0.66 | TRPM8 (0.67) | CHRM2CHRM3LMNATRPM8MEN1 | |
| SCHEMBL11437542 | 0.64 | MEN1 (0.46) | CHRM2CHRM3LMNATRPM8MEN1 | |
| SCHEMBL11456891 | 0.64 | MEN1 (0.42) | CHRM2CHRM3MEN1KMT2ASIGMAR1 | |
| SCHEMBL11438363 | 0.63 | SLC18A3 (0.33) | CHRM2CHRM3LMNA | |
| SCHEMBL11434770 | 0.63 | MEN1 (0.39) | CHRM2CHRM3MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |