Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425752 | 0.91 | KMT2A (0.42) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11432948 | 0.91 | KMT2A (0.40) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11438825 | 0.85 | MEN1 (0.41) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11424108 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1POLBKDM4ENPC1 | |
| SCHEMBL11438814 | 0.83 | MPL (0.46) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL11421974 | 0.83 | KCNMA1 (0.47) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11438898 | 0.82 | ADORA3 (0.41) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11429458 | 0.82 | ADORA3 (0.41) | KMT2AMEN1ADORA3NPC1RAB9A | |
| SCHEMBL11440926 | 0.81 | RAB9A (0.41) | KMT2AMEN1POLBGAAKDM4E | |
| SCHEMBL11428114 | 0.81 | RAB9A (0.41) | KMT2AMEN1POLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |