Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422937 | 0.89 | NPC1 (0.58) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11760548 | 0.88 | KMT2A (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11433446 | 0.86 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11428763 | 0.85 | NPC1 (0.62) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11423367 | 0.84 | HPGD (0.61) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11433673 | 0.83 | HPGD (0.52) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11431377 | 0.83 | RAB9A (0.62) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11421988 | 0.83 | KMT2A (0.55) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11426141 | 0.83 | KMT2A (0.63) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11440904 | 0.82 | HSD17B10 (0.52) | KMT2AMEN1MAPTTDP1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |