Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454403 | 0.88 | CARM1 (0.49) | DRD3CARM1PRMT6MAOBMAOA | |
| SCHEMBL11446735 | 0.86 | KMT2A (0.49) | — | |
| SCHEMBL11454661 | 0.85 | CARM1 (0.49) | DRD3CARM1PRMT6MAOBMAOA | |
| SCHEMBL11465879 | 0.84 | CARM1 (0.54) | DRD3CARM1PRMT6DRD2SLC18A3 | |
| SCHEMBL11455011 | 0.84 | DRD4 (0.58) | DRD3DRD2SIGMAR1 | |
| SCHEMBL11454487 | 0.81 | MEN1 (0.48) | DRD3OPRM1DRD2 | |
| SCHEMBL11446412 | 0.79 | HTR1A (0.59) | DRD2 | |
| SCHEMBL11466052 | 0.77 | OPRM1 (0.43) | DRD3OPRM1DRD2 | |
| SCHEMBL11446001 | 0.76 | GFER (0.61) | DRD3DRD2SIGMAR1 | |
| SCHEMBL11447143 | 0.76 | CARM1 (0.59) | DRD3OPRM1CARM1PRMT6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |