Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234461 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL512004 | 0.73 | — | — | |
| SCHEMBL11441247 | 0.73 | MEN1 (0.50) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL10206836 | 0.72 | TDP1 (0.43) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL916360 | 0.70 | MAPK1 (0.59) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL10999263 | 0.69 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HIF1ATDP1CYP3A4 | |
| SCHEMBL10857974 | 0.69 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL31217749 | 0.68 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| Benzoquinone SCHEMBL9092436 | 0.68 | MAPT (0.46) | ALDH1A1HSD17B10TSHRMAPK1TP53 | |
| SCHEMBL27660168 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183955-A | Troponyl-oxamic acid derivatives for treating allergic conditions | Ayerst. McKenna & Harrison Limited (CA) | 1980-01-15 | — | — | US | disclosed |
| US-4125625-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-11-14 | — | — | US | disclosed |
| US-4057556-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1977-11-08 | — | — | US | disclosed |