Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208745 | 0.99 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL17338966 | 0.87 | LGMN (0.49) | ALDH1A1TSHRALOX15MAPK1POLB | |
| SCHEMBL2253218 | 0.85 | SMN1; SMN2 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL11170137 | 0.78 | MEN1 (0.36) | ALDH1A1TSHRMAPK1KMT2AMEN1 | |
| SCHEMBL2431486 | 0.76 | LMNA (0.51) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL31601392 | 0.76 | LMNA (0.51) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL12519547 | 0.75 | ALOX15 (0.49) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL23091547 | 0.74 | TSHR (0.48) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL20562726 | 0.74 | ALOX15 (0.57) | ALDH1A1TSHRALOX15MAPK1KMT2A | |
| SCHEMBL10939987 | 0.74 | ALOX15 (0.45) | ALDH1A1TSHRALOX15MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221800-A | ANTIALLERGENS, ANTIHISTAMINES | MILES LABORATORIES, INC. (US) | 1980-09-09 | — | — | US | disclosed |