Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20875262 | 0.93 | NTRK1 (0.52) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL1085490 | 0.93 | ALDH1A1 (0.50) | ATMALDH1A1LMNAHTTMAPT | |
| SCHEMBL10060307 | 0.92 | LMNA (0.50) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL121957 | 0.91 | TDP1 (0.53) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL1134831 | 0.91 | ATM (0.49) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL29419144 | 0.91 | TDP1 (0.53) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL4095614 | 0.90 | ATM (0.43) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL527999 | 0.89 | ATM (0.45) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL10061459 | 0.89 | NTRK1 (0.48) | ATMNTRK1ALDH1A1LMNAHTT | |
| SCHEMBL29419096 | 0.89 | NTRK1 (0.56) | ATMNTRK1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015649-B | Method for producing aryl carboxamides | BASF SE | 2013-06-19 | — | — | CN | claimed |
| EP-2285779-B1 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-03-27 | — | — | EP | claimed |
| US-8350046-B2 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-01-08 | — | — | US | claimed |
| CN-102015649-A | Method for producing aryl carboxamides | BASF SE | 2011-04-13 | — | — | CN | claimed |
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | BASF SE | 2011-03-03 | — | — | US | claimed |
| EP-2496560-B1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2015-04-22 | — | — | EP | disclosed |
| EP-2496561-B1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8598222-B2 | Method for preparing 1,3,4-substituted pyrazol compounds | BASF SE (DE) | 2013-12-03 | — | — | US | disclosed |
| US-8592578-B2 | Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters | BASF SE (DE) | 2013-11-26 | — | — | US | disclosed |
| US-8586750-B2 | Method for the production of halogen-substituted 2-(aminomethylidene)-3-oxobutyric acid esters | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| CN-102015649-B | Method for producing aryl carboxamides | BASF SE | 2013-06-19 | — | — | CN | disclosed |
| US-20130041147-A1 | Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters | BASF SE (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20110172436-A1 | Method for preparing 1,3,4-substituted pyrazol compounds | BASF SE (EP) | 2011-07-14 | — | — | US | disclosed |
| WO-2011054732-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011054733-A1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| CN-102015649-A | Method for producing aryl carboxamides | BASF SE | 2011-04-13 | — | — | CN | disclosed |
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | BASF SE | 2011-03-03 | — | — | US | disclosed |
| US-20110046371-A1 | PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS | BASF SE (DE) | 2011-02-24 | — | — | US | disclosed |
| US-20110040096-A1 | Method for the Production of Halogen-Substituted 2-(aminomethylidene)-3-oxobutyric Acid Esters | BASF SE (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20100184994-A1 | Method for Producing Difluoromethyl-Substituted Pyrazole Compounds | BASF SE (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 | ATM 3784/4885NTRK1 1464/4885ALDH1A1 2124/4885 |
| US-20110172436-A1 | Method for preparing 1,3,4-substituted pyrazol compounds | IPO8, P2RX4, IPO11 | ATM 1732/4885NTRK1 3921/4885ALDH1A1 1798/4885 |
| US-20100184994-A1 | Method for Producing Difluoromethyl-Substituted Pyrazole Compounds | NR4A1, NR4A3, NR3C1 | ATM 4646/4885NTRK1 904/4885ALDH1A1 426/4885 |
| US-20130041147-A1 | Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters | FFAR3, CBR3, NMBR | ATM 4575/4885NTRK1 256/4885ALDH1A1 1418/4885 |
| US-20110046371-A1 | PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS | FFAR3, CBR3, NMBR | ATM 4575/4885NTRK1 256/4885ALDH1A1 1418/4885 |
| US-20110040096-A1 | Method for the Production of Halogen-Substituted 2-(aminomethylidene)-3-oxobutyric Acid Esters | AADAC, CBR3, AOC3 | ATM 3917/4885NTRK1 1557/4885ALDH1A1 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.