Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20875262 | 0.93 | NTRK1 (0.52) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL1145015 | 0.93 | ATM (0.46) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL10060307 | 0.92 | LMNA (0.50) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL28930105 | 0.92 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL31427520 | 0.92 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL121957 | 0.91 | TDP1 (0.53) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL1134831 | 0.91 | ATM (0.49) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL29419144 | 0.91 | TDP1 (0.53) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL31427500 | 0.91 | RAB9A (0.46) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL31427523 | 0.91 | ABCG2 (0.51) | ALDH1A1LMNAHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110891940-A | Process for preparing pyrazole-4-carboxamide derivatives | 日本凡凯姆股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-8211828-B2 | Fungicidal mixtures of 1-methylpyrazol-4-ylcarboxanilides and azolopyrimidinylamines | BASF SE (DE) | 2012-07-03 | — | — | US | disclosed |
| US-8153819-B2 | Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20110105331-A1 | Method of Plant Growth Promotion Using Amide Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100035753-A1 | Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides | BASF SE (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20090318291-A1 | Fungicidal mixtures of 1-methylpyrazol-4-ylcarboxanilides and azolopyrimidinylamines | BASF SE (DE) | 2009-12-24 | — | — | US | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-20080293798-A1 | Fungicidal Mixtures Comprising Substituted 1-Methylpyrazol-4-Ylcarboxanilides | BASF AKTIENGELSELLSCHAFT (DE) | 2008-11-27 | — | — | US | disclosed |
| WO-2008064780-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2008-06-05 | — | — | WO | disclosed |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| WO-2008014955-A2 | FUNGICIDAL COMPOUNDS AND COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-07 | — | — | WO | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318291-A1 | Fungicidal mixtures of 1-methylpyrazol-4-ylcarboxanilides and azolopyrimidinylamines | ERG28, AZI2, CYP51A1 | ALDH1A1 1162/4885LMNA 1883/4885HTT 3330/4885 |
| US-20080293798-A1 | Fungicidal Mixtures Comprising Substituted 1-Methylpyrazol-4-Ylcarboxanilides | CBR3, CBR1, CTRL | ALDH1A1 2217/4885LMNA 1795/4885HTT 1265/4885 |
| US-20100056477-A1 | FUNGICIDAL MIXTURES OF AMIDINYLPHENYL COMPOUNDS | NIT2, MLN, ACR | ALDH1A1 3823/4885LMNA 2519/4885HTT 526/4885 |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | CBR3, DDT, CBR1 | ALDH1A1 1090/4885LMNA 3047/4885HTT 3002/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | ALDH1A1 264/4885LMNA 4600/4885HTT 4517/4885 |
| US-20100035753-A1 | Fungicidal Mixtures Comprising Substituted 1-methylpyrazol-4-ylcarboxanilides | CBR3, CBR1, HCN2 | ALDH1A1 2931/4885LMNA 2198/4885HTT 1068/4885 |
| US-20110105331-A1 | Method of Plant Growth Promotion Using Amide Compounds | MYB, GHITM, MKI67 | ALDH1A1 3041/4885LMNA 4363/4885HTT 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.