Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454737 | 0.83 | SIGMAR1 (0.43) | POLBSIGMAR1TRPM8CHRM3CHRM2 | |
| SCHEMBL11341305 | 0.80 | SIGMAR1 (0.45) | POLBSIGMAR1TRPM8MAPTHPGD | |
| SCHEMBL11572457 | 0.77 | TSHR (0.41) | POLBSIGMAR1TSHRTRPM8MAPT | |
| SCHEMBL11571013 | 0.76 | SLC18A3 (0.44) | SIGMAR1TRPM8CHRM3CHRM2CHRM5 | |
| SCHEMBL11347000 | 0.74 | SIGMAR1 (0.41) | POLBSIGMAR1TSHRTRPM8MAPT | |
| SCHEMBL11330427 | 0.73 | SLC18A3 (0.46) | SIGMAR1TRPM8L3MBTL1CHRM3CHRM2 | |
| SCHEMBL11450445 | 0.72 | TP53 (0.36) | SIGMAR1TSHRMAPTOPRM1 | |
| SCHEMBL11437590 | 0.71 | MEN1 (0.43) | TRPM8CHRM3CHRM2MEN1ALDH1A1 | |
| SCHEMBL11465401 | 0.71 | ALDH1A1 (0.43) | SIGMAR1TRPM8CHRM3CHRM2MEN1 | |
| SCHEMBL11450497 | 0.70 | MAPK1 (0.40) | POLBSIGMAR1TSHRALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |