Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11461391 | 0.96 | SLC6A4 (0.40) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL11452293 | 0.85 | L3MBTL1 (0.39) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL11462636 | 0.84 | L3MBTL1 (0.39) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL11464674 | 0.81 | TSPO (0.36) | HTR6TSHRSCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL11452939 | 0.73 | RAD52 (0.40) | SLC6A2TSHRHSD17B10POLBRAD52 | |
| SCHEMBL11464649 | 0.73 | HTR6 (0.46) | HTR6L3MBTL1HSD17B10NPC1RAB9A | |
| Binedaline SCHEMBL49440 | 0.71 | L3MBTL1 (0.42) | HTR6L3MBTL1HSD17B10BRD4 | |
| Binedaline SCHEMBL29393236 | 0.71 | L3MBTL1 (0.42) | HTR6L3MBTL1HSD17B10BRD4 | |
| Binedaline SCHEMBL5957158 | 0.70 | L3MBTL1 (0.41) | HTR6L3MBTL1HSD17B10BRD4 | |
| SCHEMBL11452382 | 0.69 | L3MBTL1 (0.40) | HTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |