Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | PRKACG | P22612 | 2/20 | 0.39 |
| ▸ | PRKACB | P22694 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | PRKCB | P05771 | 3/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Binedaline SCHEMBL49440 | 0.91 | L3MBTL1 (0.42) | L3MBTL1KDRHTR6HTR7 | |
| Binedaline SCHEMBL29393236 | 0.91 | L3MBTL1 (0.42) | L3MBTL1KDRHTR6HTR7 | |
| Binedaline SCHEMBL5957158 | 0.90 | L3MBTL1 (0.41) | L3MBTL1KDRHTR6HTR7 | |
| SCHEMBL11465337 | 0.84 | RXRA (0.41) | HTR6LSSHTR7KDM4E | |
| Hydrochloric Acid SCHEMBL11452275 | 0.83 | MAT2A (0.50) | HTR6KDM4E | |
| SCHEMBL11452293 | 0.82 | L3MBTL1 (0.39) | L3MBTL1HTR6 | |
| Hydrochloric Acid SCHEMBL11462636 | 0.81 | L3MBTL1 (0.39) | L3MBTL1HTR6 | |
| SCHEMBL11399845 | 0.79 | DNM2 (0.42) | L3MBTL1KDM4E | |
| SCHEMBL11464649 | 0.78 | HTR6 (0.46) | L3MBTL1HTR6KDM4E | |
| SCHEMBL11454352 | 0.78 | MAT2A (0.39) | L3MBTL1HTR6HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | claimed |