Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Binedaline SCHEMBL49440 | 0.80 | L3MBTL1 (0.42) | HTR6HSD17B10BRD4L3MBTL1 | |
| Binedaline SCHEMBL29393236 | 0.80 | L3MBTL1 (0.42) | HTR6HSD17B10BRD4L3MBTL1 | |
| SCHEMBL11461065 | 0.80 | HTT (0.46) | HTR6HSD17B10BRD4L3MBTL1SMN1; SMN2 | |
| Binedaline SCHEMBL5957158 | 0.79 | L3MBTL1 (0.41) | HTR6HSD17B10BRD4L3MBTL1HTT | |
| SCHEMBL11452382 | 0.78 | L3MBTL1 (0.40) | HTR6L3MBTL1KDM4E | |
| SCHEMBL11452293 | 0.77 | L3MBTL1 (0.39) | HTR6HSD17B10BRD4L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL11462636 | 0.76 | L3MBTL1 (0.39) | HTR6HSD17B10BRD4L3MBTL1NPC1 | |
| SCHEMBL28705670 | 0.75 | SLC6A2 (0.49) | HTR6KDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL1310255 | 0.75 | IMPDH2 (0.64) | HTR6HSD17B10BRD4HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL11461391 | 0.74 | SLC6A4 (0.40) | HTR6HSD17B10BRD4L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |