Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461068 | 0.91 | CSF1R (0.39) | MAT2AL3MBTL1CSF1RHTR7CYP1A2 | |
| Binedaline SCHEMBL29393236 | 0.86 | L3MBTL1 (0.42) | L3MBTL1HTR7HTR6MEN1KMT2A | |
| Binedaline SCHEMBL49440 | 0.86 | L3MBTL1 (0.42) | L3MBTL1HTR7HTR6MEN1KMT2A | |
| Binedaline SCHEMBL5957158 | 0.85 | L3MBTL1 (0.41) | L3MBTL1HTR7HTR6 | |
| SCHEMBL11465337 | 0.80 | RXRA (0.41) | MAT2AHTR7HTR6KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11452275 | 0.79 | MAT2A (0.50) | MAT2ACYP1A2CYP2D6CYP2C19HTR6 | |
| SCHEMBL11452382 | 0.78 | L3MBTL1 (0.40) | L3MBTL1HTR7HTR6KDM4E | |
| SCHEMBL11452293 | 0.74 | L3MBTL1 (0.39) | L3MBTL1HTR6MAPT | |
| Hydrochloric Acid SCHEMBL11461487 | 0.74 | MAT2A (0.40) | MAT2AHTR7CYP1A2CYP2D6HTR6 | |
| Hydrochloric Acid SCHEMBL11462636 | 0.73 | L3MBTL1 (0.39) | L3MBTL1HTR6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |