Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452382 | 0.84 | L3MBTL1 (0.40) | HTR6KDM4ELSSHTR7 | |
| Hydrochloric Acid SCHEMBL11452275 | 0.84 | MAT2A (0.50) | HTR6MAPTSMN1; SMN2MAT2ACHEK1 | |
| SCHEMBL11454352 | 0.80 | MAT2A (0.39) | HTR6MAPTMAT2AKDM4EHTR7 | |
| Binedaline SCHEMBL49440 | 0.76 | L3MBTL1 (0.42) | HTR6HTR7 | |
| Binedaline SCHEMBL29393236 | 0.76 | L3MBTL1 (0.42) | HTR6HTR7 | |
| Binedaline SCHEMBL5957158 | 0.75 | L3MBTL1 (0.41) | HTR6HTR7 | |
| Hydrochloric Acid SCHEMBL11464674 | 0.75 | TSPO (0.36) | HTR6SMN1; SMN2TSPOKDM4EGSK3B | |
| Hydrochloric Acid SCHEMBL11452185 | 0.75 | MAT2A (0.50) | HTR6MAPTSMN1; SMN2MAT2ACHEK1 | |
| Hydrochloric Acid SCHEMBL11461487 | 0.75 | MAT2A (0.40) | HTR6MAPTMAT2ASLC6A4KDM4E | |
| SCHEMBL11461068 | 0.73 | CSF1R (0.39) | HTR6MAPTMAT2AKDM4EHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |