Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457926 | 1.00 | CA2 (0.57) | CA2CA1CA4CA9MAPT | |
| SCHEMBL10716650 | 0.78 | MAPT (0.78) | CA2CA1CA4CA9MAPT | |
| SCHEMBL10716672 | 0.76 | ALDH1A1 (0.50) | CA2CA1CA4CA9MAPT | |
| SCHEMBL11564392 | 0.75 | AKR1C3 (0.48) | CA2CA1CA4PKMALDH1A1 | |
| SCHEMBL11564387 | 0.75 | AKR1C3 (0.48) | CA2CA1CA4PKMALDH1A1 | |
| SCHEMBL4516541 | 0.73 | NAPRT (0.54) | MAPTALDH1A1NPC1KMT2AHTT | |
| SCHEMBL14135580 | 0.72 | RECQL (0.45) | CA2CA1CA4CA9MAPT | |
| SCHEMBL13856976 | 0.72 | RECQL (0.45) | CA2CA1CA4CA9MAPT | |
| SCHEMBL10717891 | 0.71 | MAPT (1.00) | CA2CA1CA4CA9MAPT | |
| SCHEMBL18871131 | 0.70 | ALDH1A1 (0.46) | MAPTPKMALDH1A1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191576-A | SULFONYL-SUBSTITUTED PYRROLIDINE, OXAZOLIDINE OR THIAZOLIDINE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-03-04 | — | — | US | disclosed |