Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716650 | 0.88 | MAPT (0.78) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10717698 | 0.84 | MAPT (0.72) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10719158 | 0.83 | MAPT (0.71) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10716463 | 0.78 | MAPT (0.64) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10731823 | 0.75 | MAPT (0.59) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL11785559 | 0.75 | MAPT (0.59) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10730781 | 0.74 | MAPT (0.58) | MAPTALDH1A1NPC1PKMMEN1 | |
| SCHEMBL10730622 | 0.73 | MAPT (0.57) | MAPTALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL10716377 | 0.72 | MAPT (0.56) | MAPTALDH1A1NPC1PKMKMT2A | |
| SCHEMBL10716583 | 0.72 | MAPT (0.56) | MAPTALDH1A1NPC1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |