Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578419 | 0.75 | TRPV1 (0.51) | TRPV1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5270294 | 0.75 | AKR1C2 (0.58) | TRPV1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8686345 | 0.73 | TRPV1 (0.50) | TRPV1KMT2AMEN1AKR1C2MAPT | |
| SCHEMBL11832981 | 0.72 | TRPV1 (0.51) | TRPV1HTTKMT2AMEN1AKR1C2 | |
| SCHEMBL1181214 | 0.72 | CTSV (0.86) | CTSVCTSLMAPK1HTTKMT2A | |
| SCHEMBL4231077 | 0.69 | ALDH1A1 (0.61) | TRPV1KMT2AMEN1AKR1C2MAPT | |
| SCHEMBL14019351 | 0.69 | ALDH1A1 (0.65) | TRPV1KMT2AMEN1AKR1C2MAPT | |
| SCHEMBL8122137 | 0.69 | TRPV1 (0.45) | TRPV1KMT2AMEN1AKR1C2MAPT | |
| SCHEMBL9400558 | 0.68 | MAPT (0.54) | CTSVCTSLHTTL3MBTL1KMT2A | |
| SCHEMBL28048707 | 0.68 | KMT2A (0.59) | CTSVCTSLHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181740-A | Indolyl acetic acid derivative | PIERREL S.P.A. (IT) | 1980-01-01 | — | — | US | disclosed |