Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270294 | 0.84 | AKR1C2 (0.58) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL8796396 | 0.81 | TRPV1 (0.46) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL4231077 | 0.78 | ALDH1A1 (0.61) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL14019351 | 0.78 | ALDH1A1 (0.65) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL8578425 | 0.76 | AKR1C2 (0.54) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL11458358 | 0.75 | CTSV (0.51) | TRPV1AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL8681641 | 0.75 | AKR1C2 (0.70) | AKR1C2ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL31676640 | 0.75 | AKR1C2 (0.70) | AKR1C2ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL29123288 | 0.75 | MAPT (0.47) | TRPV1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL8877049 | 0.75 | TRPV1 (0.51) | TRPV1AKR1C2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |