Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480981 | 0.94 | HSD11B1 (0.56) | HTR2AHSD11B1ALDH1A1 | |
| SCHEMBL11479693 | 0.84 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1 | |
| SCHEMBL11471644 | 0.80 | MAPT (0.56) | KMT2AALDH1A1 | |
| SCHEMBL11463532 | 0.79 | MC4R (0.47) | KMT2AHTR2AALDH1A1MEN1 | |
| SCHEMBL11470824 | 0.75 | OPRL1 (0.53) | — | |
| SCHEMBL11462953 | 0.75 | OPRM1 (0.58) | HTR2AHSD11B1KCNH2ALDH1A1 | |
| SCHEMBL11854451 | 0.73 | SIGMAR1 (0.48) | KMT2AKCNH2ALDH1A1SLC18A3 | |
| SCHEMBL11463659 | 0.72 | DRD3 (0.44) | — | |
| SCHEMBL11480374 | 0.72 | KCNA5 (0.56) | KMT2AALDH1A1MEN1 | |
| SCHEMBL11462098 | 0.72 | SIGMAR1 (0.39) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235914-A | ANTIPSYCHOTIC, HYPOTENSIVE, DEPRESSANTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-11-25 | — | — | US | disclosed |