Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465350 | 1.00 | F10 (0.52) | F10MEN1KMT2ANPC1TRPV1 | |
| SCHEMBL11472627 | 0.87 | RAB9A (0.59) | NPC1POLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11472624 | 0.87 | RAB9A (0.59) | NPC1POLBTAS1R3TAS1R1TAS1R2 | |
| Bromadoline SCHEMBL10697265 | 0.86 | MLYCD (0.46) | MEN1KMT2ANPC1TAS1R3TAS1R1 | |
| SCHEMBL11464453 | 0.86 | SSTR3 (0.58) | NPC1TAS1R3TAS1R1TAS1R2MLYCD | |
| Bromadoline SCHEMBL1817292 | 0.86 | MLYCD (0.46) | MEN1KMT2ANPC1TAS1R3TAS1R1 | |
| SCHEMBL11464454 | 0.86 | SSTR3 (0.58) | NPC1TAS1R3TAS1R1TAS1R2MLYCD | |
| Bromadoline SCHEMBL1817293 | 0.86 | MLYCD (0.46) | MEN1KMT2ANPC1TAS1R3TAS1R1 | |
| SCHEMBL10340084 | 0.85 | SSTR3 (0.48) | NPC1TAS1R3TAS1R1TAS1R2MLYCD | |
| SCHEMBL10340083 | 0.85 | SSTR3 (0.48) | NPC1TAS1R3TAS1R1TAS1R2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215114-A | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be | THE UPJOHN COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4197308-A | Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides | THE UPJOHN COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4192885-A | Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides | THE UPJOHN COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4179501-A | Analgesic N-(2-aminocycloaliphatic)azidobenzamides | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4153717-A | 260/332.2 R | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4152459-A | Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides | THE UPJOHN COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4148914-A | Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |