Bromadoline

Bromadoline

SCHEMBL1817292

CN(C)[C@H]1CCCC[C@@H]1NC(=O)c1ccc(Br)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MLYCD O95822 1/20 0.46
▸ HDAC3 O15379 2/20 0.46
▸ HDAC1 Q13547 2/20 0.46
▸ HDAC2 Q92769 2/20 0.46
▸ SSTR3 P32745 2/20 0.44
▸ TAS1R3 Q7RTX0 3/20 0.44
▸ TAS1R2 Q8TE23 3/20 0.44
▸ TAS1R1 Q7RTX1 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ OPRM1 P35372 1/20 0.43
▸ OPRD1 P41143 1/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromadoline SCHEMBL1817293 1.00 MLYCD (0.46) MLYCDHDAC3HDAC1HDAC2SSTR3
Bromadoline SCHEMBL10697265 1.00 MLYCD (0.46) MLYCDHDAC3HDAC1HDAC2SSTR3
Bromadoline SCHEMBL124529 0.92 ALDH1A1 (0.46) MLYCDHDAC3HDAC1HDAC2SSTR3
SCHEMBL11472624 0.87 RAB9A (0.59) MLYCDSSTR3TAS1R3TAS1R2TAS1R1
SCHEMBL11472627 0.87 RAB9A (0.59) MLYCDSSTR3TAS1R3TAS1R2TAS1R1
SCHEMBL11464454 0.86 SSTR3 (0.58) MLYCDSSTR3TAS1R3TAS1R2TAS1R1
SCHEMBL11465463 0.86 F10 (0.52) MLYCDTAS1R3TAS1R2TAS1R1KMT2A
SCHEMBL11464453 0.86 SSTR3 (0.58) MLYCDSSTR3TAS1R3TAS1R2TAS1R1
SCHEMBL11465350 0.86 F10 (0.52) MLYCDTAS1R3TAS1R2TAS1R1KMT2A
SCHEMBL10340084 0.85 SSTR3 (0.48) MLYCDSSTR3TAS1R3TAS1R2TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3560484-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2019-10-30 — — EP claimed
EP-3423034-B1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G L PHARMA GMBH (AT) 2019-07-10 — — EP claimed
EP-3423034-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2019-01-09 — — EP claimed
EP-3210596-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION G.L. Pharma GmbH (AT) 2017-08-30 — — EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 — — EP claimed
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 — — US disclosed
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices TEIKOKU PHARMA USA, INC. (US) 2026-01-20 — — US disclosed
US-20250366979-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF METHODIST HOSPITAL (US) 2025-12-04 — — US disclosed
US-20250367232-A1 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY HUTCHINSON FRED CANCER RES (US) 2025-12-04 — — US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 — — US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 — — US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 — — US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK MLYCD 2907/4885HDAC3 2876/4885HDAC1 3531/4885
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices OPRD1, OPRK1, OPRM1 MLYCD 4782/4885HDAC3 4155/4885HDAC1 4160/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 MLYCD 2030/4885HDAC3 3908/4885HDAC1 3771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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