Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364033 | 0.85 | ALDH1A1 (0.47) | ALDH1A1RECQLPPARALMNAKDM1A | |
| SCHEMBL7999767 | 0.82 | CASR (0.42) | ALDH1A1PPARALTA4H | |
| SCHEMBL10968500 | 0.81 | LTA4H (0.44) | ALDH1A1RECQLPPARALMNAKDM1A | |
| SCHEMBL11285190 | 0.81 | HDAC3 (0.42) | ALDH1A1RECQLPPARALMNAKDM1A | |
| SCHEMBL11665128 | 0.79 | LMNA (0.41) | ALDH1A1RECQLPPARALMNAKDM1A | |
| SCHEMBL27276974 | 0.78 | LMNA (0.47) | ALDH1A1RECQLPPARALMNACYP2D6 | |
| SCHEMBL97005 | 0.78 | LMNA (0.47) | ALDH1A1RECQLPPARALMNACYP2D6 | |
| SCHEMBL11095913 | 0.76 | LMNA (0.45) | ALDH1A1RECQLPPARALMNACYP2D6 | |
| SCHEMBL10516249 | 0.75 | MAPT (0.49) | ALDH1A1RECQLPPARALMNAKDM1A | |
| SCHEMBL12983709 | 0.75 | ALDH1A1 (0.48) | ALDH1A1RECQLPPARALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006718-A1 | 1.2.4-Triazolidine-3.5-dione derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |