Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465579 | 0.82 | ALDH1A1 (0.48) | LTA4HPPARAALDH1A1 | |
| SCHEMBL11285190 | 0.82 | HDAC3 (0.42) | PPARGCYP2C19LTA4HPPARAALDH1A1 | |
| SCHEMBL11273926 | 0.78 | TDP1 (0.41) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL10968500 | 0.78 | LTA4H (0.44) | CYP2C19LTA4HPPARAALDH1A1 | |
| SCHEMBL29364033 | 0.78 | ALDH1A1 (0.47) | CYP2C19LTA4HPPARAMEN1ALDH1A1 | |
| SCHEMBL11665128 | 0.77 | LMNA (0.41) | CYP2C19LTA4HPPARAALDH1A1 | |
| SCHEMBL114480 | 0.76 | TDP1 (0.43) | POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL97005 | 0.75 | LMNA (0.47) | CYP2C19LTA4HPPARAALDH1A1 | |
| SCHEMBL27276974 | 0.75 | LMNA (0.47) | CYP2C19LTA4HPPARAALDH1A1 | |
| SCHEMBL28174030 | 0.75 | FDPS (0.37) | POLBNPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000010994-A1 | PROCESS FOR THE PREPARATION OF 2-(ARYLOXYMETHYL)-2,5,7,8-TETRAMETHYLCHROMAN-6-OLS | SANKYO COMPANY, LIMITED (JP) | 2000-03-02 | — | — | WO | claimed |
| WO-2000010994-A1 | PROCESS FOR THE PREPARATION OF 2-(ARYLOXYMETHYL)-2,5,7,8-TETRAMETHYLCHROMAN-6-OLS | SANKYO COMPANY, LIMITED (JP) | 2000-03-02 | — | — | WO | disclosed |