Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116043 | 0.86 | CSNK1A1 (0.58) | KMOCLK1CLK2DYRK1ACLK4 | |
| SCHEMBL2944816 | 0.82 | CLK1 (0.60) | KMOCLK1CLK2DYRK1ACLK4 | |
| SCHEMBL5593110 | 0.81 | AGTR1 (0.68) | KMOCTSSKDM4EKDM1AXDH | |
| SCHEMBL2788482 | 0.81 | CCNT1 (0.63) | KMODYRK1ACTSSCDK2CCNT1 | |
| SCHEMBL5465537 | 0.80 | KMO (0.61) | KMOALDH1A1AURKAPIK3CDPIK3CA | |
| SCHEMBL4738297 | 0.79 | PLK1 (0.68) | KMOCLK1CLK2DYRK1ACLK4 | |
| SCHEMBL11266115 | 0.79 | MAPT (0.52) | KMOCTSSKDM4EALDH1A1KDM1A | |
| SCHEMBL25336406 | 0.78 | CAMK2D (0.69) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL4737084 | 0.78 | SYK (0.62) | KMOCLK1CLK2DYRK1ACLK4 | |
| SCHEMBL30554563 | 0.78 | CAMK2D (0.69) | CLK1CLK2DYRK1ACLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |