Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12559239 | 0.78 | GPR35 (0.38) | TDP1ALDH1A1PKM | |
| SCHEMBL4577239 | 0.71 | MCL1 (0.41) | TDP1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL2866739 | 0.70 | CYP1A2 (0.42) | TDP1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL347935 | 0.67 | TSHR (0.59) | TDP1ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL8869893 | 0.67 | MCL1 (0.38) | TDP1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL31423771 | 0.67 | LMNA (0.42) | TDP1ALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL1760867 | 0.67 | KMT2A (0.49) | TDP1ALDH1A1TSHRL3MBTL1KMT2A | |
| Cyclopropane SCHEMBL11657479 | 0.65 | CYP1A2 (0.38) | TDP1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7317416 | 0.65 | TDP1 (0.58) | TDP1ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL28300921 | 0.65 | TSHR (0.53) | TDP1ALDH1A1TSHRL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4219482-A | Process for preparing thiophene and furan derivatives | LABAZ (FR) | 1980-08-26 | — | — | US | disclosed |