SCHEMBL1146850

SCHEMBL1146850

Cc1cc(O)c(Br)cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.55
ALOX12 P18054 3/20 0.55
KDM4E B2RXH2 2/20 0.55
MAPT P10636 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
G6PD P11413 1/20 0.55
CYP2C9 P11712 1/20 0.55
PKM P14618 1/20 0.55
HPGD P15428 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 1/20 0.55
CCR6 P51684 1/20 0.55
HIF1A Q16665 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446755 1.00 ALOX15 (0.55) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL12572587 0.89 ALOX15 (0.48) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL23230056 0.86 ALOX15 (0.50) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL5698265 0.86 ALOX15 (0.43) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL282020 0.83 ALOX15 (0.55) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL30283411 0.83 ALOX15 (0.48) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL482183 0.83 ALOX15 (0.48) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL6743198 0.83 ALOX15 (0.40) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL10907457 0.83 ALOX15 (0.42) ALOX15ALOX12KDM4EMAPTALDH1A1
SCHEMBL70123 0.82 MAPT (0.75) ALOX15ALOX12KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9604929-B2 Functionalized carbon nanoparticles and functional polymer fibers prepared using the same KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-03-28 US claimed
US-20150204009-A1 FUNCTIONALIZED CARBON NANOPARTICLES AND FUNCTIONAL POLYMER FIBERS PREPARED USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-07-23 US claimed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
CN-109715728-B Adducts and uses thereof 亨斯迈先进材料美国有限责任公司 2021-11-30 CN disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
CN-111801388-A High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2020-10-20 CN disclosed
CN-109337066-B Reactive and easily-soluble rigid chain polymer and preparation method and composition thereof 浙江大学 2020-08-11 CN disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
US-20190211202-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-11 US disclosed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
US-20130144015-A1 EPOXY RESIN ADDUCTS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
EP-2563835-A1 EPOXY POLYCYCLOPENTADIENE COMPOUNDS Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
US-20130046067-A1 POLYCYCLOPENTADIENE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-21 US disclosed
WO-2012050688-A2 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-19 WO disclosed
WO-2012047420-A2 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-12 WO disclosed
WO-2011136843-A1 EPOXY POLYCYCLOPENTADIENE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
US-20110046321-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2011-02-24 US disclosed
US-20110040046-A1 ADDUCTS OF EPOXY RESINS AND PROCESS FOR PREPARING THE SAME BLUE CUBE IP LLC 2011-02-17 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046321-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME ALKBH2, GNE, ALKBH3 ALOX15 558/4885ALOX12 263/4885KDM4E 376/4885
US-20130046067-A1 POLYCYCLOPENTADIENE COMPOUNDS ERCC1, ERCC5, ERCC2 ALOX15 140/4885ALOX12 58/4885KDM4E 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.