Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30283411 | 0.89 | ALOX15 (0.48) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL482183 | 0.89 | ALOX15 (0.48) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL23230056 | 0.86 | ALOX15 (0.50) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL68996 | 0.86 | ALOX15 (0.43) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL1146850 | 0.83 | ALOX15 (0.55) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL12572587 | 0.83 | ALOX15 (0.48) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL10907457 | 0.83 | ALOX15 (0.42) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL6743198 | 0.83 | ALOX15 (0.40) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL29446755 | 0.83 | ALOX15 (0.55) | ALOX15KDM4EMAPTCYP3A4ALDH1A1 | |
| SCHEMBL120851 | 0.82 | ALDH1A1 (0.42) | CYP3A4ALDH1A1HPGDMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240200-A | Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-06-25 | — | — | CN | claimed |
| CN-113527618-B | Preparation method and application of flame-retardant flatulence slow-rebound combined polyether polyol | 南京金栖化工集团有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-113527618-A | Preparation method and application of flame-retardant flatulence slow-rebound combined polyether polyol | 南京金栖化工集团有限公司 | 2021-10-22 | — | — | CN | claimed |
| US-12269814-B2 | Process for preparing a compound useful to treat mycoses | PULMOCIDE LIMITED (GB) | 2025-04-08 | — | — | US | disclosed |
| WO-2025070947-A1 | NOVEL PHTHALAZINE DERIVATIVE COMPOUND AS SOS1 INHIBITOR, AND USE THEREOF | 한미약품 주식회사 | 2025-04-03 | — | — | WO | disclosed |
| EP-4511114-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | Vertex Pharmaceuticals Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-118240200-A | Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-06-25 | — | — | CN | disclosed |
| CN-114805054-B | Synthesis method of gemfibrozil Ji Xiu derivative | 浙江精进药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-11905230-B2 | Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2024-02-20 | — | — | US | disclosed |
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
| EP-1891080-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1890768-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |
| WO-2006128056-A2 | NOVEL PHOSPHINIC ACID-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006128055-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| EP-1689383-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | Metabasis Therapeutics, Inc. (US) | 2006-08-16 | — | — | EP | disclosed |
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
| US-20060046980-A1 | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS, INC. | 2006-03-02 | — | — | US | disclosed |
| WO-2005051298-A2 | NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS | METABASIS THERAPEUTICS, INC. (US) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | ALOX15 4734/4885KDM4E 965/4885MAPT 2339/4885 |
| US-11905230-B2 | Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament | SLC5A1, PYGL, GPR119 | ALOX15 691/4885KDM4E 995/4885MAPT 2913/4885 |
| US-20060046980-A1 | Novel phosphorus-containing thyromimetics | PYGL, THRA, THOP1 | ALOX15 1968/4885KDM4E 4102/4885MAPT 3512/4885 |
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | TRPV1, SCN3A, KCNN3 | ALOX15 694/4885KDM4E 4346/4885MAPT 2089/4885 |
| US-12269814-B2 | Process for preparing a compound useful to treat mycoses | C1R, CBR1, CBR3 | ALOX15 2400/4885KDM4E 2809/4885MAPT 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.