Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281110 | 0.82 | HRH3 (0.39) | IDO1 | |
| SCHEMBL11276656 | 0.82 | ALDH1A1 (0.37) | MAPTDAOSLC5A1SLC5A2IDO1 | |
| SCHEMBL11370488 | 0.82 | MAPT (0.36) | MAPTLMNADAOSLC5A1SLC5A2 | |
| SCHEMBL11362552 | 0.80 | MAPT (0.43) | MAPTDAORHEBDBHMPO | |
| SCHEMBL11361264 | 0.78 | LTA4H (0.44) | MEN1KMT2ASLC5A1SLC5A2MPO | |
| SCHEMBL1491971 | 0.74 | — | — | |
| SCHEMBL11362714 | 0.70 | DAO (0.40) | DAODBHMPOIDO1 | |
| SCHEMBL11632014 | 0.69 | MEN1 (0.47) | MAPTMEN1KMT2ANPC1LMNA | |
| SCHEMBL8992959 | 0.69 | IDO1 (0.46) | MAPTMEN1KMT2ALMNAIDO1 | |
| SCHEMBL11685074 | 0.67 | MEN1 (0.53) | MAPTMEN1KMT2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229352-A | Benzylpyrrolylmethyl esters of cyclopropane carboxylic acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |