Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478406 | 0.85 | ACHE (0.38) | DRD2DRD3ACHEPTGIRPTGDR | |
| SCHEMBL9117266 | 0.81 | GPR88 (0.42) | ACHEPTGIRPTGDROPRM1POLB | |
| SCHEMBL15955871 | 0.79 | KMT2A (0.48) | ACHEOPRM1POLBTSHRCHRM5 | |
| SCHEMBL9071941 | 0.79 | KMT2A (0.44) | PARP10POLBALOX5 | |
| SCHEMBL14577947 | 0.79 | TSHR (0.49) | DRD2DRD3CA1CA2PARP1 | |
| SCHEMBL11156756 | 0.76 | KEAP1 (0.54) | CA1CA2PARP1PARP10PARP2 | |
| SCHEMBL9071787 | 0.76 | QPCT (0.46) | ACHEPARP10POLBALOX5 | |
| SCHEMBL3033986 | 0.75 | OPRM1 (0.49) | OPRM1 | |
| SCHEMBL7534269 | 0.75 | TSHR (0.46) | DRD2DRD3CA1CA2PARP1 | |
| SCHEMBL11725723 | 0.74 | CA1 (0.43) | DRD2DRD3CA1CA2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202974-A | Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |
| US-4202974-A | Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |