Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | RNF4 | P78317 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14577947 | 0.81 | TSHR (0.49) | TSHRCA1CA2PARP10PARP1 | |
| SCHEMBL7534719 | 0.80 | ALOX5 (0.39) | TSHRALOX5TP53SMN1; SMN2 | |
| SCHEMBL11156756 | 0.79 | KEAP1 (0.54) | TSHRCA1CA2PARP10PARP1 | |
| SCHEMBL5682214 | 0.78 | HTT (0.49) | TSHRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL11725723 | 0.76 | CA1 (0.43) | TSHRCA1CA2PARP10PARP1 | |
| SCHEMBL11470004 | 0.75 | DRD2 (0.46) | TSHRCA1CA2PARP10PARP1 | |
| SCHEMBL3470955 | 0.73 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL7828136 | 0.72 | TSHR (0.44) | TSHRBCL2A1RNF4PDK2ALOX5 | |
| SCHEMBL22501255 | 0.72 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL5545725 | 0.72 | RPS6KA2 (0.45) | TSHRCA1CA2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200395-A1 | UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009088-A1 | UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR | KIRIN BEER KABUSHIKI KAISHA (JP) | 2001-02-08 | — | — | WO | disclosed |