Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545025 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL1235539 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL1701715 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL3208419 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7545108 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL2822938 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7541388 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7548607 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL2128896 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL905418 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075187-B | Carbonyl pyrazole antitumor compound as well as preparation method and application thereof | 山东大学 | 2023-05-12 | — | — | CN | claimed |
| CN-115974886-A | Macrocyclic lactam compound containing dihydrobenzofuran skeleton and preparation method thereof | 国科大杭州高等研究院 | 2023-04-18 | — | — | CN | claimed |
| CN-107922352-B | Process for preparing protein deacetylase inhibitors | 埃斯泰隆制药公司 | 2021-08-06 | — | — | CN | claimed |
| EP-3303304-B1 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS INC (US) | 2019-11-20 | — | — | EP | claimed |
| CN-107619407-B | Bis- target spot inhibitor of HDAC and VEGFR based on pazopanib structure and its preparation method and application | 山东大学 | 2019-05-24 | — | — | CN | claimed |
| US-10144714-B2 | Methods of making protein deacetylase inhibitors | ACETYLON PHARMACEUTICALS, INC. (US) | 2018-12-04 | — | — | US | claimed |
| EP-3303304-A1 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | Acetylon Pharmaceuticals, Inc. (US) | 2018-04-11 | — | — | EP | claimed |
| WO-2016200930-A9 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS, INC. (US) | 2017-02-23 | — | — | WO | claimed |
| WO-2016200930-A1 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS, INC. (US) | 2016-12-15 | — | — | WO | claimed |
| US-20160355486-A1 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS, INC. | 2016-12-08 | — | — | US | claimed |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | Jubilant Epicore LLC (US) | 2025-11-25 | — | — | US | disclosed |
| EP-3455204-B1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | Jubilant Epicore LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC | 2025-10-02 | — | — | US | disclosed |
| CN-119569743-A | Compound based on 6-methylfuro [2,3-d ] pyrimidine-4 (3H) -ketone structure, and preparation method and application thereof | 沈阳药科大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-114380751-B | Indanamine derivatives, preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-4244947-A | TREATMENT OF ACROMEGALY AND DIABETES | AYERST MCKENNA AND HARRISON INC. (CA) | 1981-01-13 | — | — | US | disclosed |
| US-4191754-A | ANTIDIABETIC AGENTS, INHIBIT RELEASE OF INSULIN, GLUCAGON AND GROWTH HORMONE | MERCK & CO., INC. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4161521-A | Somatostatin analogs | MERCK & CO., INC. (US) | 1979-07-17 | — | — | US | disclosed |
| US-4102888-A | VASODILATORS, ANTITHROMBITIC | MERCK & CO., INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4059587-A | 8-AZA-9-OXO-11-THIA-PROSTANOIC ACID DERIVATIVES; VASODILATORS, ANTICLOTTING, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10144714-B2 | Methods of making protein deacetylase inhibitors | HDAC1, HDAC6, AADAC | TSHR 4078/4885PAOX 1153/4885LMNA 2636/4885 |
| US-20250302815-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | PTPN1, PTPN2, PTPN18 | TSHR 538/4885PAOX 358/4885LMNA 4758/4885 |
| US-20160355486-A1 | METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS | HDAC1, HDAC6, AADAC | TSHR 4078/4885PAOX 1153/4885LMNA 2636/4885 |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | HDAC1, HDAC11, HDAC2 | TSHR 2400/4885PAOX 733/4885LMNA 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.