SCHEMBL905418

SCHEMBL905418

COC(=O)CCCCCCCCCCCN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.64
PAOX Q6QHF9 4/20 0.56
LMNA P02545 4/20 0.55
ALDH1A1 P00352 2/20 0.55
KMT2A Q03164 2/20 0.52
RECQL P46063 2/20 0.52
MEN1 O00255 1/20 0.52
PLG P00747 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147174 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545025 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL1235539 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL1701715 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL3208419 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545108 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL2822938 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7541388 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7548607 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL2128896 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220296549-A1 Small Molecule Agents, Compositions, and Formulations, for Internal Use, Displaying Inhibitory Activity Against Gram-positive and/or Gram-negative Organisms NATUREZA, INC. (US) 2022-09-22 US claimed
US-11351134-B2 Small molecule agents, compositions, and formulations, for internal use, displaying inhibitory activity against gram-positive and/or gram-negative organisms NATUREZA PRODUCTS, INC. (US) 2022-06-07 US claimed
CN-114409893-A Method for synthesizing polyamide 阿肯马法国公司 2022-04-29 CN claimed
US-11299588-B2 Polyamide synthesis method ARKEMA FRANCE (FR) 2022-04-12 US claimed
EP-3068818-B1 POLYAMIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2021-01-20 EP claimed
US-10745721-B2 Process for reacting a carboxylic acid ester EVONIK OPERATIONS GMBH (DE) 2020-08-18 US claimed
EP-3664794-A1 LAURIC ACID DERIVATIVES DISPLAYING INHIBITORY ACTIVITY AGAINST GRAM-POSITIVE AND/OR GRAM-NEGATIVE ORGANISMS Natureza, Inc. (US) 2020-06-17 EP claimed
WO-2019033125-A9 LAURIC ACID DERIVATIVES DISPLAYING INHIBITORY ACTIVITY AGAINST GRAM-POSITIVE AND/OR GRAM-NEGATIVE ORGANISMS NATUREZA, INC. (US) 2020-04-02 WO claimed
US-20190046483-A1 Small Molecule Agents, Compositions, and Formulations, for Internal Use, Displaying Inhibitory Activity Against Gram-Positive and/or Gram-Negative Organisms NATUREZA, INC. (US) 2019-02-14 US claimed
WO-2019033125-A1 LAURIC ACID DERIVATIVES DISPLAYING INHIBITORY ACTIVITY AGAINST GRAM-POSITIVE AND/OR GRAM-NEGATIVE ORGANISMS NATUREZA, INC. (US) 2019-02-14 WO claimed
US-20160280854-A1 POLYAMIDE SYNTHESIS METHOD ARKEMA FRANCE (FR) 2016-09-29 US claimed
CN-103459033-B Liquid cation exchanger 赢创德固赛有限公司 2016-08-10 CN claimed
US-9315443-B2 Liquid cation exchanger EVONIK DEGUSSA GMBH (DE) 2016-04-19 US claimed
US-20140039210-A1 LIQUID CATION EXCHANGER EVONIK DEGUSSA GMBH (DE) 2014-02-06 US claimed
CN-103459033-A Liquid cation exchanger EVONIK DEGUSSA GMBH 2013-12-18 CN claimed
WO-2012156151-A1 METHOD FOR ω-AMINOCARBOXYLIC ACID CONDENSATION EVONIK DEGUSSA GMBH (DE) 2012-11-22 WO claimed
WO-2012110125-A1 LIQUID CATION EXCHANGER EVONIK DEGUSSA GMBH (DE) 2012-08-23 WO claimed
WO-2012110124-A1 LIQUID CATION EXCHANGER EVONIK DEGUSSA GMBH (DE) 2012-08-23 WO claimed
EP-2489432-A2 Fluid cationic exchanger Evonik Degussa GmbH (DE) 2012-08-22 EP claimed
US-3933873-A Preparation of omega-aminoalkanoic acids TEXACO INC. (US) 1976-01-20 US claimed