Sugi Predict

Sugi Predict / Compounds / SCHEMBL2822938

SCHEMBL2822938

SCHEMBL2822938

COC(=O)CCCCCCCCCCCCCN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.64
▸ PAOX Q6QHF9 4/20 0.56
▸ LMNA P02545 4/20 0.55
▸ ALDH1A1 P00352 2/20 0.55
▸ KMT2A Q03164 2/20 0.52
▸ RECQL P46063 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ PLG P00747 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ SLC6A2 P23975 1/20 0.52
▸ SLC6A3 Q01959 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2D6 P10635 1/20 0.48
▸ NFKB1 P19838 1/20 0.48
▸ BLM P54132 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147174 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545025 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL1235539 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL1701715 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL3208419 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545108 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7541388 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7548607 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL2128896 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL905418 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595495-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2026-04-07 — — US disclosed
US-20250019731-A1 Methods Of Producing Omega-Hydroxylated Fatty Acid Derivatives AGAIN BIO APS (DK) 2025-01-16 — — US disclosed
CN-105378486-B Process for producing OMEGA-hydroxylated fatty acid derivatives 基因组股份公司 2024-05-14 — — CN disclosed
US-11981952-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2024-05-14 — — US disclosed
CN-116854604-A Preparation method of omega-amino fatty acid methyl ester and long-chain nylon 中国科学院微生物研究所 2023-10-10 — — CN disclosed
US-20220062258-A1 Heterocyclic derivatives MERCK PATENT GMBH (DE) 2022-03-03 — — US disclosed
US-20210071212-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES GENOMATICA, INC. (US) 2021-03-11 — — US disclosed
EP-3745133-A1 METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES Genomatica, Inc. (US) 2020-12-02 — — EP disclosed
WO-2020152067-A1 HETEROCYCLIC DERIVATIVES MERCK PATENT GMBH (DE) 2020-07-30 — — WO disclosed
US-10711288-B2 Methods of producing omega-hydroxylated fatty acid derivatives GENOMATICA, INC. (US) 2020-07-14 — — US disclosed
US-7041673-B2 High speed metabolism; antiepileptic agents; anesthetics; central nervous system disorders; anxiolytic agents ARYX THERAPEUTICS, INC. (US) 2006-05-09 — — US disclosed
US-20040167143-A1 Ultrashort acting hypnotic barbiturates MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC 2004-08-26 — — US disclosed
US-6683086-B2 DERIVATIVES OF BARBITURIC AND THIOBARBITURIC ACIDS; RAPIDLY METABOLIZED BY BLOOD AND TISSUE ENZYMES TO FORM POLAR METABOLITES WITH NO HYPNOTIC ACTIVITY AND WHICH ARE RAPIDLY ELIMINATED ARYX THERAPEUTICS 2004-01-27 — — US disclosed
US-20030100575-A1 Ultrashort acting hypnotic barbiturates MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC 2003-05-29 — — US disclosed
EP-1276728-A2 ULTRASHORT ACTING HYPNOTIC BARBITURATES ARYx Therapeutics (US) 2003-01-22 — — EP disclosed
EP-0885886-B1 PYRIDINECARBOXAMIDE DERIVATIVES NISSHIN SEIFUN GROUP INC (JP) 2002-05-29 — — EP disclosed
US-20020013330-A1 Ultrashort acting hypnotic barbiturates MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC 2002-01-31 — — US disclosed
WO-2001081319-A2 ULTRASHORT ACTING HYPNOTIC BARBITURATES ARYX THERAPEUTICS (US) 2001-11-01 — — WO disclosed
US-5972943-A N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-10-26 — — US disclosed
EP-0885886-A1 NOVEL PYRIDINECARBOXAMIDE DERIVATIVES Nisshin Flour Milling Co., Ltd. (JP) 1998-12-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167143-A1 Ultrashort acting hypnotic barbiturates GABRR1, GABRA1, GABRR2 TSHR 493/4885PAOX 834/4885LMNA 4742/4885
US-12595495-B2 Methods of producing omega-hydroxylated fatty acid derivatives CYP4F11, CYP2F1, CYP4Z1 TSHR 1330/4885PAOX 684/4885LMNA 3439/4885
US-20030100575-A1 Ultrashort acting hypnotic barbiturates GABRR1, GABRA1, GABRR2 TSHR 493/4885PAOX 834/4885LMNA 4742/4885
US-20020013330-A1 Ultrashort acting hypnotic barbiturates GABRR1, GABRA1, GABRR2 TSHR 493/4885PAOX 834/4885LMNA 4742/4885
US-20220062258-A1 Heterocyclic derivatives XIAP, UBQLN1, UBQLN2 TSHR 4395/4885PAOX 1562/4885LMNA 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.