Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147174 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7545025 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL1235539 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL3208419 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7545108 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL2822938 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7541388 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL7548607 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL2128896 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A | |
| SCHEMBL905418 | 1.00 | TSHR (0.64) | TSHRPAOXLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974886-A | Macrocyclic lactam compound containing dihydrobenzofuran skeleton and preparation method thereof | 国科大杭州高等研究院 | 2023-04-18 | — | — | CN | claimed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | claimed |
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-115141123-B | Compound, preparation method thereof and application thereof in preparation of dual inhibitors of histone deacetylase and epoxide hydrolase | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |
| US-20240024488-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240024488-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240024488-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-01-25 | — | — | US | disclosed |
| EP-4247381-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115974886-A | Macrocyclic lactam compound containing dihydrobenzofuran skeleton and preparation method thereof | 国科大杭州高等研究院 | 2023-04-18 | — | — | CN | disclosed |
| EP-2585432-A1 | SYNTHESIS OF OMEGA-AMINO CARBOXYLIC ACIDS AND THEIR ESTERS FROM UNSATURATED FATTY ACID DERIVATIVES | Evonik Degussa GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-8377661-B2 | Method for synthesising omega-amino-alkanoic acids or the esters thereof from natural fatty acids | ARKEMA FRANCE (FR) | 2013-02-19 | — | — | US | disclosed |
| WO-2011160730-A1 | SYNTHESIS OF OMEGA-AMINO CARBOXYLIC ACIDS AND THEIR ESTERS FROM UNSATURATED FATTY ACID DERIVATIVES | EVONIK DEGUSSA GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| US-20110224454-A1 | METHOD FOR THE SYNTHESIS OF AN OMEGA-AMINO ACID OR ESTER STARTING FROM A MONOUNSATURATED FATTY ACID OR ESTER | ARKEMA FRANCE (FR) | 2011-09-15 | — | — | US | disclosed |
| US-20110105774-A1 | METHOD FOR SYNTHESISING 9-AMINONONANOIC ACID OR THE ESTERS THEREOF FROM NATURAL UNSATURATED FATTY ACIDS | ARKEMA FRANCE (FR) | 2011-05-05 | — | — | US | disclosed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | disclosed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224454-A1 | METHOD FOR THE SYNTHESIS OF AN OMEGA-AMINO ACID OR ESTER STARTING FROM A MONOUNSATURATED FATTY ACID OR ESTER | FASN, ELOVL6, ELOVL1 | TSHR 3566/4885PAOX 113/4885LMNA 1199/4885 |
| US-20110105774-A1 | METHOD FOR SYNTHESISING 9-AMINONONANOIC ACID OR THE ESTERS THEREOF FROM NATURAL UNSATURATED FATTY ACIDS | FASN, ALOX5, ALOX15 | TSHR 4452/4885PAOX 82/4885LMNA 740/4885 |
| US-20240024488-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | TSHR 4351/4885PAOX 136/4885LMNA 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.