SCHEMBL1235539

SCHEMBL1235539

COC(=O)CCCCCCCCCCN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.64
PAOX Q6QHF9 4/20 0.56
LMNA P02545 4/20 0.55
ALDH1A1 P00352 2/20 0.55
KMT2A Q03164 2/20 0.52
RECQL P46063 2/20 0.52
MEN1 O00255 1/20 0.52
PLG P00747 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147174 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545025 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL1701715 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL3208419 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7545108 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL2822938 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7541388 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL7548607 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL2128896 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A
SCHEMBL905418 1.00 TSHR (0.64) TSHRPAOXLMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515885-B1 PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES UMICORE AG & CO KG (DE) 2023-12-13 EP claimed
CN-109982995-B Preparation of amino acids and amino acid derivatives 优美科股份公司及两合公司 2022-09-30 CN claimed
US-10913960-B2 Biotechnological production of omega-functionalised carboxylic acids and esters thereof EVONIK OPERATIONS GMBH (DE) 2021-02-09 US claimed
US-10774035-B2 Preparation of amino acids and amino acid derivatives UMICORE AG & CO. KG (DE) 2020-09-15 US claimed
US-20190276388-A1 PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES UMICORE AG & CO KG (DE) 2019-09-12 US claimed
EP-3515885-A1 PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES UMICORE AG & CO. KG (DE) 2019-07-31 EP claimed
CN-109982995-A PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES 优美科股份公司及两合公司 2019-07-05 CN claimed
WO-2018057290-A1 PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES MATERIA, INC. (US) 2018-03-29 WO claimed
EP-3173478-A1 BIOTECHNOLOGICAL PRODUCTION OF OMEGA-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF Evonik Degussa GmbH (DE) 2017-05-31 EP claimed
US-20170145448-A1 BIOTECHNOLOGICAL PRODUCTION OF omega-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF EVONIK DEGUSSA GMBH (DE) 2017-05-25 US claimed
JP-11343337-A None JP disclosed
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
US-12486468-B2 Method for the preparation of omega-amino-carboxylic acids and derivatives thereof VERSALIS S.P.A. (IT) 2025-12-02 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
US-20250136887-A1 METHOD FOR THE PREPARATION OF OMEGA-AMINO-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF VERSALIS S.P.A. (IT) 2025-05-01 US disclosed
US-5659052-A APPLYING TO SKIN TO IMPROVE BARRIER FUNCTIONS OF HORNY LAYER KAO CORPORATION (JP) 1997-08-19 US disclosed
EP-0761644-A2 Amide derivatives and their use in cosmetic composition KAO CORPORATION (JP) 1997-03-12 EP disclosed
US-5468888-A Lupane derivatives, their preparation and the pharmaceutical compositions which contain them RHONE-POULENC RORER S.A. (FR) 1995-11-21 US disclosed
EP-0623124-A1 AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME Kao Corporation (JP) 1994-11-09 EP disclosed
WO-1994012490-A2 AMIDE DERIVATIVES AND DERMATOLOGIC PREPARATIONS CONTAINING THE SAME KAO CORPORATION (JP) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190276388-A1 PREPARATION OF AMINO ACIDS AND AMINO ACID DERIVATIVES AADAT, BCAT1, BCAT2 TSHR 3293/4885PAOX 2552/4885LMNA 3915/4885
US-12486468-B2 Method for the preparation of omega-amino-carboxylic acids and derivatives thereof FADS1, ABHD6, FASN TSHR 4010/4885PAOX 396/4885LMNA 1843/4885
US-20250136887-A1 METHOD FOR THE PREPARATION OF OMEGA-AMINO-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF FADS1, ABHD6, FASN TSHR 4010/4885PAOX 396/4885LMNA 1843/4885
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL TSHR 2934/4885PAOX 640/4885LMNA 3163/4885
US-10774035-B2 Preparation of amino acids and amino acid derivatives AADAT, BCAT1, BCAT2 TSHR 3293/4885PAOX 2552/4885LMNA 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.