Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 6/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BID | P55957 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472080 | 0.96 | LMNA (0.38) | LMNATRPM8BCL2A1RAB9AKDM4E | |
| SCHEMBL11478756 | 0.82 | LMNA (0.39) | LMNATRPM8BCL2A1GAAMEN1 | |
| SCHEMBL11472079 | 0.81 | TRPM8 (0.46) | LMNATRPM8CHRM2CHRM3RAB9A | |
| SCHEMBL11472081 | 0.81 | TRPM8 (0.46) | LMNATRPM8CHRM2CHRM3RAB9A | |
| SCHEMBL11508179 | 0.78 | LMNA (0.33) | LMNATRPM8CHRM2CHRM3GAA | |
| SCHEMBL11454751 | 0.77 | OPRD1 (0.43) | RAB9AKDM4EMEN1NPC1MITF | |
| SCHEMBL11454719 | 0.76 | MEN1 (0.38) | BCL2A1CHRM2CHRM3RAB9AGAA | |
| SCHEMBL11468501 | 0.75 | CNR2 (0.37) | LMNATRPM8RAB9AKDM4EMEN1 | |
| SCHEMBL11508799 | 0.75 | TRPM8 (0.48) | TRPM8CHRM2CHRM3RAB9AKDM4E | |
| SCHEMBL11508798 | 0.75 | TRPM8 (0.48) | TRPM8CHRM2CHRM3RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | claimed |
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |