Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472080 | 0.86 | LMNA (0.38) | LMNATRPM8SIGMAR1CNR2KMT2A | |
| SCHEMBL11468501 | 0.82 | CNR2 (0.37) | LMNATRPM8SIGMAR1CNR2KMT2A | |
| SCHEMBL11472016 | 0.82 | LMNA (0.37) | LMNATRPM8SIGMAR1CNR2KMT2A | |
| SCHEMBL11347007 | 0.78 | SIGMAR1 (0.43) | SIGMAR1CNR2KMT2AMEN1NPC1 | |
| SCHEMBL11508179 | 0.78 | LMNA (0.33) | LMNATRPM8SIGMAR1CNR2GAA | |
| SCHEMBL11338200 | 0.78 | TRPM8 (0.43) | TRPM8SIGMAR1KMT2AMEN1NPC1 | |
| SCHEMBL11478753 | 0.78 | TRPM8 (0.43) | TRPM8SIGMAR1KMT2AMEN1NPC1 | |
| SCHEMBL11332175 | 0.76 | SIGMAR1 (0.42) | SIGMAR1CNR2KMT2AMEN1NPC1 | |
| Fumaric Acid SCHEMBL11332169 | 0.76 | MEN1 (0.39) | LMNASIGMAR1CNR2KMT2AMEN1 | |
| SCHEMBL11478373 | 0.74 | CNR1 (0.33) | LMNATRPM8CNR2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |