Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DUT | P33316 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140825 | 1.00 | PKM (0.55) | PKMLMNAALDH1A1DUTPOLB | |
| SCHEMBL26040211 | 0.85 | PKM (0.62) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL337057 | 0.84 | PKM (0.50) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL23873265 | 0.84 | PKM (0.60) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL11498514 | 0.83 | DUT (0.53) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL11498513 | 0.83 | DUT (0.53) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL5180755 | 0.83 | PKM (0.53) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL27004382 | 0.82 | PKM (0.40) | PKMLMNAALDH1A1DUTPOLB | |
| SCHEMBL19171430 | 0.80 | PKM (0.52) | PKMLMNAALDH1A1DUTL3MBTL1 | |
| SCHEMBL26231009 | 0.79 | PKM (0.59) | PKMLMNAALDH1A1DUTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230708-A | SYNERGISTIC | STICHTING REGA V.Z.W. (BE) | 1980-10-28 | — | — | US | disclosed |