SCHEMBL5180755

SCHEMBL5180755

O=c1ccn(CC(CO)C(O)O)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.53
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
DUT P33316 10/20 0.45
L3MBTL1 Q9Y468 1/20 0.39
CRBN Q96SW2 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11472497 0.83 PKM (0.55) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL7140825 0.83 PKM (0.55) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL23873265 0.81 PKM (0.60) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL19171430 0.77 PKM (0.52) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL25739570 0.77 PKM (0.49) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL26231009 0.76 PKM (0.59) PKMALDH1A1LMNADUTCRBN
SCHEMBL27219170 0.75 PKM (0.54) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL26040211 0.75 PKM (0.62) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL27219168 0.75 PKM (0.54) PKMALDH1A1LMNADUTL3MBTL1
SCHEMBL27219275 0.75 PKM (0.54) PKMALDH1A1LMNADUTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249548-A1 Nucleoside Analog or Salts of the Same GIFU UNIVERSITY (JP) 2007-10-25 US disclosed
EP-1798225-A1 NUCLEOSIDE ANALOGUES OR SALTS THEREOF Gifu University (JP) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249548-A1 Nucleoside Analog or Salts of the Same NSUN2, RNMT, RNGTT PKM 793/4885ALDH1A1 1694/4885LMNA 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.