SCHEMBL337057

SCHEMBL337057

O=c1ccn(CC(O)CCCO)c(=O)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.50
DUT P33316 13/20 0.49
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7140825 0.84 PKM (0.55) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL23873265 0.79 PKM (0.60) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL3079985 0.77 DUT (0.56) DUTALDH1A1LMNAL3MBTL1
SCHEMBL11474759 0.77 DUT (0.49) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL913206 0.76 DUT (0.55) DUTALDH1A1LMNAL3MBTL1
SCHEMBL5180755 0.75 PKM (0.53) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL11498513 0.75 DUT (0.53) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL11498514 0.75 DUT (0.53) PKMDUTALDH1A1LMNAL3MBTL1
SCHEMBL25368590 0.74 NAAA (0.54) DUTALDH1A1LMNAL3MBTL1
SCHEMBL24205032 0.74 NAAA (0.54) DUTALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10427125-B2 Methods for performing patterned chemistry ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-10-01 US disclosed
US-10294526-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2019-05-21 US disclosed
US-10035147-B2 Wafer with gel-based biochips for electrochemical synthesis and electrical detection of polymers INTEL CORPORATION (US) 2018-07-31 US disclosed
US-20170356044-A1 POLYMER CO-LOCATION IN SURFACE-ATTACHED BIOPOLYMERS AND ARRAYS OF BIOPOLYMERS INTEL CORP (US) 2017-12-14 US disclosed
US-9745628-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2017-08-29 US disclosed
US-20170234825-A1 HIGH THROUGHPUT BIOCHEMICAL DETECTION USING SINGLE MOLECULE FINGERPRINTING ARRAYS INTEL CORP (US) 2017-08-17 US disclosed
US-9551682-B2 High throughput biochemical detection using single molecule fingerprinting arrays INTEL CORPORATION (US) 2017-01-24 US disclosed
US-20150231633-A1 GEL-BASED BIO CHIP FOR ELECTROCHEMICAL SYNTHESIS AND ELECTRICAL DETECTION OF POLYMERS INTEL CORP (US) 2015-08-20 US disclosed
US-9096953-B2 Method for high throughput, high volume manufacturing of biomolecule micro arrays INTEL CORPORATION (US) 2015-08-04 US disclosed
US-20150212032-A1 METHOD AND APPARATUS FOR MATCH QUALITY ANALYSIS OF ANALYTE BINDING INTEL CORPORATION 2015-07-30 US disclosed
US-5631134-A POSITIONAL SEQUENCING BY HYBRIDIZATION SINGLE STRANDED NUCLEIC ACID TO FORM DETECTORS, LIGATING TARGETS, ISOLATION OF NUCLEIC ACIDS AND HYBRIDIZING NUCLEIC ACIDS THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-05-20 US disclosed
WO-1997016699-A1 PIEZOELECTRIC FORCE SENSING APPARATUS AND METHODS FOR BIOPOLYMER SEQUENCING TRUSTEES OF BOSTON UNIVERSITY (US) 1997-05-09 WO disclosed
EP-0668932-A4 POSITIONAL SEQUENCING BY HYBRIDIZATION. UNIV BOSTON (US) 1996-11-27 EP disclosed
WO-1996032504-A2 SOLID PHASE SEQUENCING OF BIOPOLYMERS TRUSTEES OF BOSTON UNIVERSITY (US) 1996-10-17 WO disclosed
US-5503980-A DETERMINING NUCLEOTIDE SEQUENCE OF NUCLEIC ACID TARGET USING NUCLEIC ACID PROBES TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-02 US disclosed
EP-0668932-A1 POSITIONAL SEQUENCING BY HYBRIDIZATION TRUSTEES OF BOSTON UNIVERSITY (US) 1995-08-30 EP disclosed
EP-0439779-B1 Process for producing optically active hydroxy lactones CHISSO CORP (JP) 1995-08-16 EP disclosed
WO-1994011530-A1 POSITIONAL SEQUENCING BY HYBRIDIZATION TRUSTEES OF BOSTON UNIVERSITY (US) 1994-05-26 WO disclosed
US-5084392-A Ester interchange reaction for hydroxy lactones CHISSO CORPORATION (JP) 1992-01-28 US disclosed
EP-0439779-A2 Process for producing optically active hydroxy lactones CHISSO CORPORATION (JP) 1991-08-07 EP disclosed