Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474569 | 0.77 | TRPM8 (0.44) | MEN1KMT2ATRPM8ALOX5NPC1 | |
| SCHEMBL8263373 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2ATRPM8ALOX5NPC1 | |
| SCHEMBL339507 | 0.72 | CES2 (0.56) | MEN1KMT2ACA12CA9TRPM8 | |
| SCHEMBL5966848 | 0.70 | TSHR (0.50) | MEN1KMT2ATRPM8ALOX5NPC1 | |
| SCHEMBL27699387 | 0.70 | CES2 (0.54) | MEN1KMT2ACA12CA9TRPM8 | |
| Hydrochloric Acid SCHEMBL68638 | 0.70 | CES2 (0.54) | MEN1KMT2ACA12CA9TRPM8 | |
| SCHEMBL2948755 | 0.70 | ALOX5 (0.72) | TRPM8ALOX5NPC1RAB9ACES2 | |
| SCHEMBL17602099 | 0.69 | FNTA (0.55) | KMT2ACA2ALOX5NPC1RAB9A | |
| SCHEMBL1077996 | 0.69 | CA12 (0.41) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11465092 | 0.69 | MLYCD (0.49) | MEN1KMT2ATRPM8SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222946-A | ANTIALLERGEN, HYPERSENSITIVITY | LILLY INDUSTRIES, LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4187232-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |