SCHEMBL11475035

SCHEMBL11475035

CN(C1CCCCC1)N1CCC(O)C1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.33
PHGDH O43175 1/20 0.33
MGLL Q99685 1/20 0.33
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ALDH1A1 P00352 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20093559 0.74
SCHEMBL391420 0.74
SCHEMBL11465448 0.74 ADH1A (0.39) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL4689592 0.74 ADH1A (0.39) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL8598786 0.74 ADH1A (0.39) FAAHPHGDHMGLLADH1CADH1A
Hydrochloric Acid SCHEMBL14634438 0.73 ADH1A (0.38) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL28136187 0.68 LMNA (0.37) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL24511489 0.68 DPP4 (0.41) FAAHPHGDHMGLLALDH1A1PKM
SCHEMBL24511675 0.68 DPP4 (0.41) FAAHPHGDHMGLLALDH1A1PKM
SCHEMBL24517987 0.68 DPP4 (0.41) FAAHPHGDHMGLLALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4215114-A Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be THE UPJOHN COMPANY (US) 1980-07-29 US disclosed
US-4197308-A Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides THE UPJOHN COMPANY (US) 1980-04-08 US disclosed
US-4192885-A Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides THE UPJOHN COMPANY (US) 1980-03-11 US disclosed
US-4179501-A Analgesic N-(2-aminocycloaliphatic)azidobenzamides THE UPJOHN COMPANY (US) 1979-12-18 US disclosed
US-4153717-A 260/332.2 R THE UPJOHN COMPANY (US) 1979-05-08 US disclosed
US-4152459-A Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides THE UPJOHN COMPANY (US) 1979-05-01 US disclosed
US-4148914-A Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides THE UPJOHN COMPANY (US) 1979-04-10 US disclosed
US-4098904-A ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES THE UPJOHN COMPANY (US) 1978-07-04 US disclosed