Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.39 |
| ▸ | ADH1C | P00326 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689592 | 1.00 | ADH1A (0.39) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL8598786 | 1.00 | ADH1A (0.39) | ADH1AADH1CFAAHPHGDHMGLL | |
| Hydrochloric Acid SCHEMBL14634438 | 0.98 | ADH1A (0.38) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL28136187 | 0.82 | LMNA (0.37) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL28698139 | 0.76 | CHRNB2 (0.30) | — | |
| SCHEMBL19465567 | 0.76 | — | — | |
| SCHEMBL11475035 | 0.74 | FAAH (0.33) | ADH1AADH1CFAAHPHGDHMGLL | |
| SCHEMBL29637669 | 0.74 | ADH1A (0.33) | ADH1AADH1CPHGDHALDH1A1LMNA | |
| SCHEMBL9651538 | 0.74 | ADH1A (0.33) | ADH1AADH1CPHGDHALDH1A1LMNA | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL9782767 | 0.68 | ADH1C (0.38) | ADH1AADH1CFAAHPHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215114-A | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be | THE UPJOHN COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4197308-A | Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides | THE UPJOHN COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4192885-A | Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides | THE UPJOHN COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4179501-A | Analgesic N-(2-aminocycloaliphatic)azidobenzamides | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4153717-A | 260/332.2 R | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4152459-A | Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides | THE UPJOHN COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |