Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598786 | 0.82 | ADH1A (0.39) | LMNAADH1CADH1AALDH1A1FAAH | |
| SCHEMBL11465448 | 0.82 | ADH1A (0.39) | LMNAADH1CADH1AALDH1A1FAAH | |
| SCHEMBL4689592 | 0.82 | ADH1A (0.39) | LMNAADH1CADH1AALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL14634438 | 0.80 | ADH1A (0.38) | LMNAADH1CADH1AALDH1A1FAAH | |
| SCHEMBL21437424 | 0.78 | MAPT (0.35) | LMNASMN1; SMN2ABHD6MAPTNPSR1 | |
| SCHEMBL8467302 | 0.73 | LMNA (0.39) | LMNASMN1; SMN2ABHD6ADH1CADH1A | |
| SCHEMBL28698139 | 0.70 | CHRNB2 (0.30) | — | |
| SCHEMBL19465567 | 0.70 | — | — | |
| SCHEMBL2606475 | 0.68 | ALOX5 (0.37) | LMNAABHD6MAPTNPSR1NPC1 | |
| SCHEMBL4375383 | 0.68 | MAPT (0.50) | LMNASMN1; SMN2ABHD6MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664973-B | Spiro-oxindole compounds and their use as therapeutic agents | 泽农医药公司 | 2017-04-19 | — | — | CN | disclosed |