Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.43 |
| ▸ | DRD5 | P21918 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11467098 | 0.82 | DRD2 (0.42) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11474291 | 0.75 | DRD1 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11467110 | 0.70 | GAA (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11457812 | 0.68 | HRH3 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11455605 | 0.68 | HRH3 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11455577 | 0.66 | SIGMAR1 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL10720684 | 0.66 | MTNR1B (0.47) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4361668 | 0.66 | ALDH1A1 (0.49) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL11051922 | 0.65 | DRD2 (0.54) | DRD1DRD2BCHEKCNH2 | |
| SCHEMBL11715371 | 0.65 | OPRK1 (0.56) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233217-A | USED AS ANALGESICS, NARCOTIC ANTAGONISTS, AND ANTIHISTAMINES | PENNWALT CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |