SCHEMBL1147729

SCHEMBL1147729

Cc1cc(Cl)cc(C(=O)N(C)C2CC2)c1NC(=O)C1CC(OS(=O)(=O)c2cccc([N+](=O)[O-])c2)=NN1c1ncccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 4/20 0.34
MALT1 Q9UDY8 3/20 0.34
HTT P42858 3/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
F2 P00734 1/20 0.34
P2RY2 P41231 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MAPK1 P28482 1/20 0.33
P2RX7 Q99572 1/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148273 0.94 MALT1 (0.36) GPR17MALT1HTTMAPTALDH1A1
SCHEMBL1148228 0.93 GPR17 (0.33) GPR17MALT1HTTMAPTF2
SCHEMBL1148355 0.91 GPR17 (0.35) GPR17MALT1HTTMAPTF2
SCHEMBL1148464 0.89 GPR17 (0.38) GPR17MALT1HTTMAPTALDH1A1
SCHEMBL1148236 0.89 MALT1 (0.35) MALT1HTTMAPTALDH1A1F2
SCHEMBL1148238 0.87 P2RY2 (0.31) GPR17MALT1P2RY2
SCHEMBL1147730 0.87 F2 (0.36) GPR17MALT1HTTMAPTALDH1A1
SCHEMBL1148360 0.86 GPR17 (0.36) GPR17MALT1HTTMAPTALDH1A1
SCHEMBL1148362 0.85 RBP4 (0.33) GPR17MALT1HTTMAPTP2RY2
SCHEMBL592001 0.83 MALT1 (0.34) MALT1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 GPR17 4172/4885MALT1 3967/4885HTT 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.